Reference Guide

Dosing Guide

How to dose every product we carry — plus the universal rules that make any nootropic work better. Find your product below or scroll the principles first.

Evidence-Based Dosing 3rd-Party Tested Updated Regularly
Nootropix Research 6 min read

Start here: four rules for everything

Consistency beats dose size

Taking the same dose at the same time daily beats a bigger, random dose. Routine is the active ingredient.

Start at the lower end

Begin at the bottom of your range for the first few days, then adjust upward once you know how you respond.

Most stacks work best with food

Unless the label says otherwise, take with a meal. Many compounds are fat-soluble and absorb far better with dietary fat.

Give it the full first month

Many compounds build over weeks. Judge the result after a consistent month, not after the first few doses.

5-HTP 100mg Capsules

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Dose
100–200 mg
Timing
Evening
Cycling
Cycle 2–3 months on, then a break
Notes
Do NOT combine with antidepressants/SSRIs or other serotonergics. Evening use supports mood and sleep.

Acetyl L-Carnitine 500mg Capsules

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Dose
500–1000 mg
Timing
Morning, empty stomach
Notes
Take before food for absorption. Provides clean energy and mental clarity.

Agmatine Sulfate 250mg Capsules

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Dose
250–500 mg
Timing
Anytime / pre-workout
Cycling
Cycle to maintain sensitivity
Notes
Start at 250 mg and assess. Commonly used pre-workout.

Agmatinsulfatpulver

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Dose
250–500 mg (use a scale)
Timing
Anytime / pre-workout
Cycling
Cycle to maintain sensitivity
Notes
Measure with a scale; start low. Commonly used pre-workout.

Alpha-GPC 250mg Capsules

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Dose
300–600 mg/day
Timing
Morning / with your racetam dose
Cycling
Not required
Notes
Choline donor. Stacks with racetams to prevent headaches and amplify effects.

Aniracetam 500mg Capsules

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Dose
750–1500 mg/day
Timing
Pre-task (AM / early PM)
Food
Take with food
Cycling
Optional; pair with a choline source
Notes
Fat-soluble — take with a meal or dietary fat. Pair with Alpha-GPC to prevent acetylcholine-depletion headaches.

Aniracetam-Pulver

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Dose
750–1500 mg (use a scale)
Timing
Pre-task (AM / early PM)
Food
Take with food
Cycling
Optional; pair with a choline source
Notes
Fat-soluble and bitter — take with food/fat. Pair with choline.

Ashwagandha KSM-66 300mg Capsules

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Dose
300–600 mg
Timing
Morning or evening, daily
Food
Take with food
Cycling
Optional 8–12 weeks on, then a short break
Notes
Cumulative adaptogen — take daily with food. Evening use can aid wind-down.

Bacopa Monnieri 300mg Capsules

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Dose
300–600 mg
Timing
Morning, with food
Food
Take with food
Notes
Cumulative — take daily with food; full memory effects appear after 4–6 weeks. Fat improves absorption.

BPC-157 500mcg Capsules

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Dose
500mcg per capsule (1 capsule)
Timing
1 capsule daily, with or without food
Cycling
Commonly used in defined research cycles (e.g. several weeks on, then a break). Follow your protocol.
Notes
Each capsule is pre-measured at 500mcg, so no reconstitution or measuring is needed. Start at the low end of your protocol and adjust as documented.

CDP-choline 250mg Capsules

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Dose
250–500 mg
Timing
Morning / with racetams
Notes
Choline donor. Pair with racetams to support acetylcholine and prevent headaches.

Coluracetam 20mg Capsules

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Dose
20–80 mg
Timing
Pre-task
Food
Take with food
Cycling
Optional; pair with a choline source
Notes
Fat-soluble — take with food. Short-acting; some split into 2–3 doses/day. Pair with choline.

Fasoracetam 20mg Capsules

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Dose
20–80 mg
Timing
Morning / pre-task
Cycling
Optional; pair with a choline source
Notes
Calm-focus racetam; some report anti-anxiety effects. Pair with a choline source.

Fladrafinil 20mg Capsules

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Dose
30–100 mg (2–5 caps)
Timing
Morning / early day
Cycling
2–3× per week, or 5 on / 2 off
Notes
Long-acting eugeroic — avoid afternoon dosing so it doesn't disrupt sleep. Not for daily use.

Fladrafinil-Pulver

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Dose
30–100 mg (use a mg scale)
Timing
Morning / early day
Cycling
2–3× per week, or 5 on / 2 off
Notes
Long-acting eugeroic; very bitter. A milligram scale is essential. Avoid afternoon use; not daily.

GABA 500mg Capsules

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Dose
500–750 mg
Timing
Evening / as needed
Notes
May cause drowsiness — do not drive if affected. Oral GABA response varies by individual.

Frequently asked questions

How do I know which dose to start with?

Start at the low end of the range on the product label or in this guide. Hold that dose for several days before increasing. Your goal is the smallest amount that produces a clear, repeatable effect.

Should I take nootropics with food?

Unless the label says otherwise, take with a meal — especially for fat-soluble compounds. Food often improves absorption and reduces stomach upset.

How long before I notice effects?

Some compounds work within hours; others build over weeks. Judge stimulant-like effects after a few consistent doses. Judge adaptogens and memory supports after a consistent month.

Can I combine multiple nootropics?

Yes, but introduce one new compound at a time. That way you can tell what changed. Stacks inherit the strictest cycling rule of any ingredient inside them.

What is cycling and when do I need it?

Cycling means planned off-days or off-weeks. Tolerance-prone compounds need it; many daily-friendly adaptogens do not. See our Cycling Guide for tier-based schedules.

How does dosing interact with cycling?

Dose sets how much on an on-day; cycling sets which days are on-days. Both belong in the same protocol. Size your bottle to your schedule, not the other way around.

What if I miss a dose?

For daily-friendly compounds, take it when you remember the same day if appropriate. For strict-cycle compounds, do not double up — return to your planned on-day schedule and use your dot-grid to stay honest.